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This 29 amino acid peptide has about 50 % homology to glucagon and is the primary circulating form in humans which has incretin activity
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Berberine lowers fasting plasma glucose by about 0.540.82 mmol/L (roughly 1015 mg/dL) and HbA1c by 0.540.63% in type 2 diabetes (28-study meta-analysis, 2,313 patients
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