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UV radiation (UVR) exposure can activate the cutaneous immune system by releasing pro-inflammatory factors, ROS, and inducing apoptosis in keratinocytes, thereby causing sterile inflammation or cancer (D'Orazio et al., 2013)
Treatments with Vit C and CoQ10, administered individually, effectively reduced MDA levels, though the combined treatment of Vit C and CoQ10 was notably more effective
Second, national supplementation and fortification programs could reduce preventable neurological and hematologic complications
In a comparative study using thigh skin in women with aged skin, participants applied topical GHK-Cu alongside vitamin C and retinoic acid over 12 weeks, with collagen improvement measured through biopsy-based markers
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