IV therapy may be appropriate when nutrient absorption is limited or when more direct support is clinically indicated
HRT Addresses: Estrogen-driven fat redistribution, muscle loss prevention, sleep disruption, hot flashes and night sweats GLP-1 Addresses: Appetite dysregulation, insulin resistance, blood sugar instability, inflammation reduction Combined Benefit: Targets both hormonal AND behavioral factors, which can help preserve lean mass while losing fat and support better energy for lifestyle changes, leading to comprehensive quality of life improvement Rather than competing approaches, hormone optimization therapy and GLP-1 therapy can work through distinct physiological pathways that reinforce each other
A.-T., Frohlich, B., Mininberg, D
Furthermore, the KDIGO 2024 guidelines cover combination therapy from the perspective of SGLT2is being first-line therapy, and long-acting GLP-1 RAs being an add-on in adults with CKD and T2D who have not achieved individualised glycaemic targets despite use of metformin and SGLT2is, or who are unable to use those medications [2]
It contains semaglutide , a GLP-1 receptor agonist that works by regulating hunger, food intake, and how the body uses insulin
