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1 Introduction Incretin peptides are secreted from the intestine after nutrient ingestion and enhance glucose-stimulated insulin secretion ( 2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D ( The mechanism underlying the impressive weight loss potential of GLP-1R agonists is primarily, if not exclusively, mediated by a reduction in energy intake

1 These injections can support energy levels, metabolism, immune health, and overall rejuvenation

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When selenium is diminished, susceptibility to infections and cancers increases because it impairs innate and adaptive immunity (140, 141)