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ADA Recommendations for GLP-1 RA in T2DM Patients The GLP-1 receptor agonists, with or without metformin based on glycemic needs, are appropriate initial therapy for patients with type 2 diabetes mellitus (T2DM) with or at high risk for atherosclerotic cardiovascular disease (ASCVD)/indicators of high-risk, heart failure (HF), or chronic kidney disease (CKD)

Since the mean/median duration for each of these studies was 100,000 patients prescribed a GLP-1RA, after propensity matching, there was reduced risk for PDAC during a 5-year observation period for GLP-1RA users compared to six categories of commonly used diabetes medication classes 44

Eating smaller meals and avoiding heavy or greasy foods may help