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The 3 mg dose is commonly used during treatment initiation to help patients adapt to therapy before dose escalation if clinically appropriate
When the fluorescent secondary antibody method was used, the sections were treated with Alexa 488- or Alexa 555-conjugated anti-mouse/rabbit IgG (1:500 dilution, Molecular Probes, Eugene, OR)
For example, some PIs have been shown to alter mitochondrial membrane potential and promote ROS production in hepatocytes and adipocytes
doi: 10.1039/D3FB00236E 103
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