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However, while ephedrine stimulates multiple alpha and beta receptors affecting the cardiovascular system, synephrine only targets beta receptors responsible for fat mobilization, making it a safer alternative by avoiding side effects like tachycardia and hypertension
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7 The phase 3 SURMOUNT-4 trial (NCT04660643), conducted by Aronne et al, included 670 participants with overweight or obesity without diabetes who were followed for 52 weeks after completing a maximum-tolerated tirzepatide lead-in regimen for 36 weeks
503B pharmacies are federally registered, follow stricter manufacturing standards, and produce larger batches closer to a drug manufacturer than a corner pharmacy
