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[1] [2] Water fasting may intensify these symptoms and increase dehydration risk, potentially leading to acute kidney injury, particularly if vomiting or diarrhoea occurs without adequate fluid intake

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Additionally, a meta-analysis of 26 trials concluded that GLP-1RAs were particularly effective in reducing macrovascular and microvascular complications, positioning them as a strong therapeutic choice for patients at risk of cardiovascular and cerebrovascular disease

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