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GLP-1 medications delay gastric emptying, which means food may remain in the stomach longer than expected despite standard fasting

Phase II Clinical Data Jastreboff 2023 (NEJM) reported 24.2% bodyweight reduction at 48 weeks - the largest effect size published for any metabolic peptide in clinical trials

clinicians in Kingsport, TN start you on a low dose and gradually increase it to minimize discomfort