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To evaluate Dihexas ability to cross the BBB and accumulate in brain regions, rats were fitted with carotid cannulas and infused with a mixture of [H]Dihexa (10 Ci) and [C]inulin (2 Ci), a vascular space marker, in 100 l of isotonic saline

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Investigational efforts also include novel drug combinations and targeted formulations, which may enhance semaglutides clinical utility and safety profile

Lv Y, Lei N, Wang D, An Z, Li G, Han F, Liu H, Liu L