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The pH, ionic strength, and perhaps even chemical reactions within the formulation might cause faster degradation of the semaglutide peptide, thereby reducing its BUD still further
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Oral semaglutide may even lead to less nausea and vomiting than once-weekly dulaglutide and once-daily lixisenatide (two less common GLP-1 injectable medications), though its nausea profile is similar to that of injectable semaglutide
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