Another group applied multi-omics analyses in PBMCs from RA patients at the start of anti-TNF- treatment and showed high expression of epiplakin 1 (EPPK1) and T-cell inhibitor chitinase-3-like 1 (CHI3L1) genes in those who responded [165]
And the reason we do that, is because theyre essentially the same thing, and we want patients to listen to our recommendations about which will create the best result, not which one costs a few dollars less
Therefore, high blood serum levels of this can be a marker of liver disease, rather than a sign that the body overall contains optimal levels of vitamin B12
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