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On the outer mitochondrial membrane, CPTI (carnitine-palmitoyl transferase I) catalyzes the transfer of medium/long-chain fatty acids esterified to coenzyme A (CoA) to L-carnitine
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Secondly, the relative orientations and distance of two membrane-proximal regions are also significantly different between these two complexes, which to a certain extent could explain why HGF and NK1 have different ability in triggering c-MET activation
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