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Description

A TUE should be sought for doses in excess of these limits

Blood was collected, from which plasma was isolated after centrifuging the blood in a 4 C centrifuge at 2000 g for 15 min

I., & Saii, Z

Watch for severe dizziness, rapid heartbeat, extreme nausea or vomiting, confusion, shaking, or inability to keep fluids down

Maintaining patients at a given dose for an additional four weeks before escalation may be appropriate if gastrointestinal symptoms are difficult to characterize