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In rats, at higher doses of empagliflozin causing maternal toxicity, malformations of limb bones increased in fetuses at 700 mg/kg/day or 154-times the 25 mg maximum clinical dose

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However, relatively little research is currently available on milk thistle's overall safety for those who are pregnant or breastfeeding, so you should first consult with a medical professional to assess its place in your regimen

10.1016/j.jacc.2024.08.038 54 PingetM.GoldenbergR.NiemoellerE.Muehlen-BartmerI.GuoH.AronsonR