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Semaglutide GLP-1 is suitable for patients with a BMI of 30+ (obesity) or 27+ (overweight) with a weight-related comorbidity

Effect of semaglutide on bone formation, resorption markers, and interleukin 6 (IL-6) Bone-specific alkaline phosphatase (BALP) is a sensitive and reliable marker of bone formation activity

These include uncertainties regarding optimal treatment duration, management of side effects, and the high cost associated with these medications