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Several classes of mood stabilizers are linked to weight gain: Antipsychotics (Atypical Antipsychotics): These are often prescribed alongside mood stabilizers to help manage mood disorders

IGF/IGFBPs level alterations in MetS have been, to some extent, observed, however the exact mechanism has not been elucidatedstill it suggests a trend towards IGF-1 local or systemic deficiency or availability

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Reactive oxygen species also perform necessary signaling and immune functions, and excessive antioxidant exposure may disrupt normal redox balance