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Consequently, the targeted inhibition of GOT1, in conjunction with its upstream and downstream pathways, or the combined inhibition of the major metabolic pathways of glutamine, has emerged as a promising novel strategy to overcome metabolic therapy resistance

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Chondroitin sulfate is the main component of glial scars, and the enzyme chondroitin sulfate ABC reduces it.[ref] Another animal study used melatonin for six weeks on sciatic nerve injuries