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Sustained inhibition of NPY/AgRP neuronal activity by FGF1
The detrimental effects of ROS on cartilage homeostasis can be effectively alleviated by augmenting cellular antioxidant activity under stress conditions, and several attempts have been made to treat OA by targeting the regulators involved in oxidative stress production in cartilage 84,85,86
Remodeling of glycolipid metabolism The antioxidant and anti-inflammatory effects of molecular hydrogen have been well documented, but the free radical scavenging properties of molecular hydrogen cannot fully explain its extensive biological effects, especially in metabolic liver diseases such as hepatic steatosis, NASH, and MASLD
However, for patients who have already reached a healthy weight, microdosing may help maintain results while potentially providing ongoing metabolic benefits with fewer side effects
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