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The expression of catalase is also altered in cancer cells, most likely to promote cell proliferation by causing genomic instability and oncogene activation
Sources: Seiwerth S;Rucman R;Turkovic B;Sever M;Klicek R;Radic B;Drmic D;Stupnisek M;Misic M;Vuletic LB;Pavlov KH;Barisic I;Kokot A;Japjec M;Blagaic AB;Tvrdeic A;Rokotov DS;Vrcic H;Staresinic M;Sebecic B;Sikiric P
All strains and plasmids are available upon request from the corresponding authors laboratory
The objective of the study was to develop a simple and sensitive spectrofluorimetric assay method for glutathione transferase using monobromobimane (MBB), a non fluorescent compound with electrophilic site
It does not appear toxic, does not accumulate in tissues, and has been well tolerated in trials
