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Conversely, FXR activation can ameliorate steatohepatitis and fibrosis by dynamically regulating lipid and glucose homeostasis in the NASH liver through cytokine-mediated mechanisms (Fiorucci et al., 2020)
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BMC Cancer (2021) 21(1):1297
After 8 weeks of treatment, the positive effects were more pronounced for all the clinical skin parameters quantified, and the fibroblasts experiment confirmed the stimulatory impact on dermal health parameters
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