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That finding suggests high-dose GLP-1 medications could potentially reach the joints and influence inflammation directly, not just help through weight loss
However, the musculoskeletal recovery picture appears more favorable
When to Switch or Adjust Your GLP-1 Treatment If you've reached an adequate dose (1.5mg2.0mg weekly for semaglutide), maintained it for 8+ weeks, followed lifestyle recommendations, and still lost less than 5% of body weight, a medication change is warranted
Researchers have also studied 50 mg of oral semaglutide, but it is not FDA-approved
Puglisi R, Tramer F, Panfili E, Micali F, Sandri G, Boitani C
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