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Nicholls NEJM 2025
Initially, the agency cited shortages of semaglutide and tirzepatide the active ingredients in the popular drugs Wegovy and Zepbound and allowed pharmacies to compound these drugs under a provision for addressing drug shortages
Specifically, for each decrease of 10 mL/min/1.73 m 2 in the eGFR, SUA increased by 0.24 mg/dL (r = 0.232, P 300 U/L were 4.31 (95% CI 1.6211.46) and 10.3 (95% CI 3.5029.90) times more likely to have hiperuricemia, respectively
Vasorelaxation at least 60% by 3 M ACh in rings pre-contracted with 3 M PE was considered endothelium intact
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