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New Drugs 13, 602605
Electrophysiological and c-Fos mapping studies in rodent models have demonstrated that amylin receptor activation in these regions inhibits gastric emptying, reduces meal size, and activates downstream satiety circuits projecting to the hypothalamic arcuate nucleus (Lutz et al., Physiology & Behavior, 2010)
This suppression of the NF-B pathway contributes to the downregulation of pro-inflammatory mediators, thereby enhancing its therapeutic efficacy in psoriasis management
The Benefit For Heart Failure With Preserved Ejection in a New Trial More than half of patients with heart failure have preserved pump function, as quantified by election fraction
This is the part that is particularly affected by the disease (the substantia nigra) so there appears to be a strong link between the two
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