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Medical conditions affecting absorption warrant particular attention : Pernicious anaemia : an autoimmune condition destroying gastric parietal cells, requiring lifelong B12 injections Gastrointestinal surgery : particularly gastric bypass, gastrectomy, or terminal ileum resection Inflammatory bowel disease : Crohn's disease affecting the terminal ileum impairs absorption Coeliac disease : untreated disease damages the small intestine, reducing B12 uptake Medication use : long-term metformin therapy (MHRA safety alert) or nitrous oxide exposure Symptoms suggesting possible B12 deficiency include : persistent fatigue, weakness, paraesthesia (pins and needles) in hands or feet, glossitis (sore, red tongue), mood changes, memory problems, or unexplained anaemia
Most research supports a daily intake in the range of: 1,000 to 2,000 mg per day for general fat loss support Up to 3,000 mg per day in certain performance-focused studies For most individuals, 1,500 to 2,000 mg daily is a practical starting point
Superior Absorption: Unlike oral supplements that degrade in the digestive system, our nasal spray bypasses the gut, delivering glutathione directly to your bloodstream and brain for maximum bioavailability
Does B12 Help You Lose Weight
Thinner individuals use 45 degrees
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