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Outcome measures histological scoring and gross visual assessment are not functional outcomes
Injection site reactions occurred at rates dramatically higher than placebo
AKT can also phosphorylate other chromatin-modifying enzymes, such as the histone methyltransferase EZH2 (H3K27 methylation) and DNA methyltransferase DNMT1, resulting in changes in function of these enzymes [90, 91]
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