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There is a C-to-T single-nucleotide polymorphism at the 718 position (rs713041) located in the 3-untranslated region of the GPX4 gene close to the predicted selenocysteine insertion sequence structure (SECIS, a region of the mRNA required for incorporation of the amino acid Sec into GPX4)
Der oxidative Stress kann entweder durch ein berangebot von aktivierten Sauerstoff-Stufen (Sauerstoff-Radikale) und/oder durch eine Verminderung jener Molekle entstehen, welche normalerweise diese Radikalenergie abzufangen vermgen und als Scavengermolekle bezeichnet werden
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