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This is a separate and still investigational line of research rather than an established use, and it should not be confused with the fat-loss mechanism that the bulk of the clinical work has focused on

Current Uncertainties and Future Challenges Regarding NAD+ Boosting in the Context of Brain Aging and Dementia

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This includes vegans and vegetarians, older adults, individuals with atrophic gastritis, pernicious anemia, gastrointestinal disorders, those who have had gastrointestinal surgery and people who take certain medications including, but not limited to, estrogen (HRT), and birth control pills