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A patient with reduced GLP-1 receptor sensitivity may need intermediate dosing between commercial pen strengths, or a patient with poor tolerability might require smaller weekly increments
At present, however, roughly 75% of Medicaid enrollees have no coverage of GLP-1s for weight loss
doi:10.1089/ars.2011.4198
Future studies should optimize treatment parameters, including formulation, dosage, timing of administration, and assessment of brain biodistribution and explore multi-target strategies combining redox modulation with interventions that directly engage synaptic plasticity, neurotrophic signaling or critical developmental windows, to achieve functional behavioral outcomes in ASD
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