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Clarifying mechanisms of action for each supplement

But even in those, the effect sizes are relatively small, and in the clinic the results are often more disappointing than the trials would suggest. Dr Whittle said due to the nature of fibromyalgia, there was unlikely to be a magic bullet or single receptor pharmacotherapeutic intervention that was broadly or substantially successful in most people with fibromyalgia

Research studies typically span up to 8 to 12 weeks, while long-term, indefinite use of TB-500 is not recommended

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