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The developmental stage of dentate granule cells dictates their contribution to seizure-induced plasticity

Members work with a personal health coach every two weeks via video-chat sessions and receive text support between sessions for nutrition, exercise, and habit-building guidance

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Researchers should anticipate that the glucagon receptor-mediated effects on energy expenditure may manifest earlier in some assays than the full appetite-suppressing effects, given the different tissue distributions of the three receptor types

Aroda, M.D., from Brigham and Women's Hospital in Boston, and colleagues randomly assigned adults with type 2 diabetes inadequately controlled with diet and exercise to receive once-weekly subcutaneous cagrilintide 2.4 mg plus semaglutide 2.4 mg, cagrilintide 1.0 mg plus semaglutide 1.0 mg, or placebo for 40 weeks (62, 63, and 64 participants, respectively)