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For example, it is known that surgical removal of subcutaneous [8] or intra-abdominal [9] adipose tissue does not improve insulin sensitivity in obese human subjects despite weight loss induction

Yes, in narrower circumstances

Morello M, Krone CL, Dickerson S, Howerth E, Germishuizen WA et al (2009) Dry-powder pulmonary insufflation in the mouse for application to vaccine or drug studies

The aim of this study was to evaluate and compare cardiac function and myocardial scarring as late gadolinium enhancement with CMR in PCD patients with carriers and healthy subjects in order to assess if current prophylactic treatment strategy should be reevaluated

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