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TDP-43-induced inflammatory responses in microglia were attenuated when treated with an IL-6 trans-signaling inhibitor in vitro , suggesting that IL-6 trans-signaling may act as a potential driver of inflammation in ALS pathogenesis (Risby-Jones et al., 2025)
Gosk S, Vermehren C, Storm G, Moos T
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Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, et al
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