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However Lillys demonstration that a GIP/GLP-1 receptor co-agonist (tirzepatide) has superior efficacy compared to selective GLP-1 receptor agonists, has renewed interest in the first incretin. Lilly rolled out their SURPASS trials to position their agent amongst existing diabetes medications and GLP-1 agonists

Nonetheless, ePA ensures that, when coverage is allowed, a patients initiation onto therapy is not prevented by paperwork, potentially capturing the drugs value

Endocrinology 137, 29682978, doi: 10.1210/endo.137.7.8770921 (1996)

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