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Heterogeneity of release probability, facilitation, and depletion at central synapses
Do BPC-157 and TB-500 have different half-lives
The absence of safety data in these populations should inform clinical decision-making and prescribing practices
The extent to which a once-weekly, continuously present amylin analogue reproduces these meal-linked effects as opposed to producing a tonic, non-pulsatile signal quite unlike physiological amylin is a genuinely open question, discussed further in our review of how cagrilintide affects gastric emptying and postprandial metabolism
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