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The neurological aspects of the disease are thought to arise from the accumulation of methylmalonyl- CoA due to the requirement of B 12 as a cofactor to the enzyme methylmalonyl-CoA mutase
However, patients with sulfa allergy should not take this injection
Adensylcobalamin is also vital in the creation and maintenance of the myelin sheath, which protects nerve cells and your brain, which methylcobalamin cant achieve (Thakkar and Billa, 2014)
The standard dose is 1000 mcg (1 mg) per month
Your healthcare provider will be able to determine the frequency of your injection needs after running some blood tests
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