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Secreted primarily in the gut in response to food intake, GLP-1 helps slow down stomach emptying, promoting a feeling of fullness and satisfaction after eating
Endocrinol Nutr 59(3):197206 Devoto F, Zapparoli L, Bonandrini R, Berlingeri M, Ferrulli A, Luzi L et al (2018) Hungry brains: a meta-analytical review of brain activation imaging studies on food perception and appetite in obese individuals
Other groups requiring careful evaluation include: Patients with a history of pancreatitis a causal relationship between incretin-based therapies and pancreatitis has not been definitively established, but UK SmPCs advise caution in those with a prior history
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