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We wondered whether inhibition of TS in cells surviving 5FU treatment promoted the observed reprogramming of mitochondria towards increased biogenesis and activity
Moreover, HPLC-MS/MS techniques allow for the precise identification and quantification of ROS byproducts, providing detailed information on the types of oxidative damage occurring within the cell
PMID 8154512.
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The peptide appears to act antagonistically on opiate receptors, significantly inhibiting the development of both opioid and alcohol dependence in animal studies
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