If you, or someone you care for, is taking GLP-1s and you notice symptoms such as severe, persistent stomach pain that may radiate to the back and may be accompanied by nausea and vomiting, then we advise you speak to a healthcare professional and report it via our yellow card scheme. Separately, the MHRA said that patients taking GLP-1s had been recruited to the Yellow Card Biobank study, a collaboration between the MHRA and Genomics England, which will investigate whether the risk of an inflamed pancreas can be influenced by an individuals genes
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They advise thorough evaluation for any history of pancreatitis, and careful monitoring for gastrointestinal side effects, which, while usually transient, can be a barrier to adherence
Semaglutide is generally more effective than Qsymia for weight management but is also more expensive
Severe heartburn is manageable with appropriate medical therapy in the vast majority of cases