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Despite this short plasma half-life, the downstream GH pulse it triggers lasts 2-3 hours, and the resulting IGF-1 elevation persists for 12-18 hours
doi:10.1002/jcsm.13213 Pickart L, Vasquez-Soltero JM, Margolina A
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They lack the dependence potential of stimulants or benzodiazepines
When breaks make sense vs continuous use The decision between GHK-Cu cycling with breaks versus continuous indefinite application depends on individual goals, budget constraints, treatment response patterns, and philosophical approach to skincare interventions, with different strategies suiting different user profiles and priorities creating no single optimal approach applicable universally
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