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Provisional data
If you prefer a supplemental option, Liposomal Vitamin C is one place to look
Plasma half-life is about 159-195 hours, or roughly 6.6-8.1 days
Briefly, recombinant PDI protein (0.4 M) was incubated with indicated compounds at 37 C for 1 h in sodium phosphate buffer (100 mM sodium phosphate, 2 mM EDTA and 8 M DTT, pH 7.0)
These results indicate that the increased amount of non-12-OH FXR-antagonistic BAs consequent to the decrease in CYP8B1 expression after T3 treatment potentiates GLP-1 production by deactivating the intestinal FXR, thereby improving glucose homeostasis via the augmentation of insulin secretion
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