In contrast, there is some evidence of an enhancement of the maximum absorption via intrinsic factor, by up to a factor of 2, when the vitamin B12 is accompanied by food, but this is not consistently observed and probably only applies when the food quantity and vitamin B12 dose are sufficient to slow the passage of the vitamin B12 through the small intestine enough (about three hours or more) to allow each intrinsic factor receptor to absorb two molecules of vitamin B12 from the oral dose rather than one
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This allows for a safer and more effective procedure with minimised risks of adverse effects
Nausea and vomiting was the most common side effect, with the worst five antidepressants being duloxetine (odds ratio [OR] 4.33), vortioxetine (OR 4.28), levomilnacipran (OR 3.81), venlafaxine (OR 3.52), and desvenlafaxine (OR 3.51)
This means the body can actually use the nutrient rather than just digesting it as simple amino acids