doi:10.1021/acs.biochem.7b00492 48
Mice Male and female mice (aged 812-week-old) were co-housed 25 mice per cage in individually ventilated cages in our facility at the Medizinisch-Theoretisches Zentrum (MTZ) at the Medical Faculty of the Technical University of Dresden (TU Dresden)

Indications and Usage for Cyanocobalamin Cyanocobalamin is indicated for vitamin B 12deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
The hypothyroid blood vessels are unable to relax properly, contributing to hypertension
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