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Shutara Y, Koga Y, Fujita K, Takeuchi H, Mochida M, Takemasa K (1996)
After supplementing with glutathione for 12 weeks while participating in a randomized, double-blind, placebo-controlled trial, healthy female subjects reported improved skin elasticity and fewer wrinkles
Starting directly from DL-carnitine, L-carnitine can be obtained through chemical resolution using resolving agents such as camphoric acid, N-acetyl-D-glutamic acid, or ethyl benzoyl-L-(+)-tartaric acid
This strategy not only improves intracellular DOX concentrations but also reduces off-target distribution to organs such as the heart, liver and kidneys, potentially widening the therapeutic window
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