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In the efficacy estimand, the company reported average body-weight reductions of 19.0% at 4 mg, 25.9% at 9 mg, and 28.3% at 12 mg at 80 weeks, compared with 2.2% for placebo

According to FDA prescribing information and clinical trial data, these side effects are generally dose-dependent and tend to diminish over time as patients develop tolerance to the medication

The listed 45 lb weight specification signals a substantial recorded shipping or catalog entry

Dynamic clonal equilibrium and predetermined cancer risk in Barretts oesophagus