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95% CI [0.51.9]), with a slight increase in diastolic BP (mean difference: +0.6 mmHg

Although Mounjaro has not been studied in human pregnancy, it shouldnt be used by pregnant women as it has been shown to cause reproductive toxicity in animal studies

It requires cofactors, specific enzymes, and recycling nutrients

The authors systematically searched PubMed and Embase from inception to 1 May 2025 for cohort studies comparing the effect of combination therapy with SGLT2 inhibitor or GLP-1 RA monotherapy on (cardiovascular) mortality and cardiovascular or kidney endpoints in individuals with type 2 diabetes

We also detected a loss of the neuronal cell marker NeuN and an activation of cleaved caspase-3 (Fig