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In cases of failed convergence with log-binomial regression (for total AE and other AE), a modified Poisson regression was used to calculate RRs with 95% CIs from robust standard errors estimated using the sandwich estimator 41
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Because oral options sit directly within the stomach to be absorbed, some patients report a higher frequency of upper gastrointestinal symptoms, including acid reflux, indigestion, and localised stomach discomfort during the morning fasting window
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