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Evening timing may also improve sleep quality in some patients through choline's role as a precursor to acetylcholine, the neurotransmitter involved in REM sleep regulation

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Similarly, semaglutide ameliorates doxorubicin-induced cardiotoxicity by reducing BNIP3-mediated mitochondrial dysfunction through the PI3K/AKT pathway, enhancing mitochondrial function and reducing cardiac injury (Li et al., 2024), potentiating its clinical application in cardiovascular diseases