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Shimmura C, Suzuki K, Iwata Y, Tsuchiya KJ, Ohno K, Matsuzaki H, et al
A CVOT meta-analysis and an umbrella review of meta-analyses of RCTs reported that GLP-1 RAs reduce the risk of combined fatal and non-fatal MI when compared to placebo (HR = 0.90, 95%CI = 0.830.98
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![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
