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Bottom line: New GLP-1 medicines may be only a few years away, but in the meantime, proven options like Ozempic and Wegovy already offer major health benefits

Acknowledgements This work was supported by the Canadian Institutes of Health Research (CIHR

Your prescriber may consider: Slowing the dose escalation schedule to allow more time for gastrointestinal adaptation Temporarily reducing to a previously tolerated dose or maintaining the 1.7 mg dose if 2.4 mg is not tolerated Prescribing anti-emetics for short-term nausea management in selected cases

Hippisley-Cox, J., Coupland, C

Strength training and follow-ups boost their chances